ALBUQUERQUE, N.M. (AP) – Authorities say a crackdown on narcotics trafficking in northwestern New Mexico has led to arrests of multiple people charged in federal indictments.

The U.S. Attorney’s Office for New Mexico says the multi-agency investigation was launched in response to an increase in methamphetamine trafficking in the Shiprock area of the Navajo Nation.

The office says six people who were arrested Wednesday made initial appearances Thursday in federal court in Farmington. Two other people named remain at large.

The indictments stem from undercover agents’ drug purchases.

In addition to the arrests, operations Wednesday included searches of residences in Shiprock and Kirtland.

The office says authorities seized more than 2.5 pounds of methamphetamine, 10 guns, $1,600 in cash and a vehicle.

Numerous federal, state, tribal, county and municipal agencies participated in the investigation.